Table 1. Frequency of LOH in cases of sporadic breast and ovarian carcinomas observed for markers at the 11q23–q24 locus.
No. of cases with LOH/no. of informative cases (% LOH)
|
|||
---|---|---|---|
Locus (% HET)*† | Breast | Ovary | Total |
D11S4094 (71) | 5/14 (36) | 3/11 (27) | 9/25 (36) |
D11S1353 (74) | 5/14 (36) | 5/16 (31) | 10/30 (33) |
D11S4144 (75) | 5/19 (26) | 2/16 (13) | 7/35 (20) |
D11S1328 (64) | 7/16 (44) | 5/13 (38) | 12/29 (41) |
D11S933 (82) | 5/15 (33) | 1/16 (6) | 6/31 (19) |
D11S934 (89) | 2/14 (14) | 3/18 (17) | 5/32 (16) |
Marker sequences available at www.ncbi.nlm.nih.gov.
Marker heterozygosities obtained from www.cephb.fr.