Table 5. The structure of rearrangement breakpoints isolated in a tsa1 Δ mutant.
Breakpoint type/breakpoint sequences | |
---|---|
Telomere addition | |
GTGTTACTACTAGGATTTGGCGTGG: gtgtgggtgtgggtgtg (34867) | |
TGTGTATGGGCACAAACCCTTG: ggtgtgggtgtggtgtgggtgtgggtg (34422) | |
ACTACTAGGATTTGGCGTGG: gtgtggtgtgtgggtgtgggtgtgg (34867) | |
ACTAGGATTTGGCGTGGATG: ggtgtgggtgtggtgtgggtgtggtgtgtg (34864) | |
TTTTTGTATGGTTTGTGGTGCTGGG: tgtggtgtgggtg (32708) | |
AGGGTTTCTGTGTGGTTTCCGGGTG: tggtgtggtg (33820) | |
ATGGCTATTAAATATCACTG: ggtgtgggtgtgggtgtggtgtggtgtggt (32098) | |
CGGTATGATGTAGTTTTTAAATGTG: ggtgtgggtgtggtgtgg (34538) | |
Large deletion | |
V (34241) | (34184) |
ATACGATTACTCCAGTTCCTCTTACAAGAAAT: GCATAAAAATAGTTACAATTAATTAG | |
ACTAAGGTTTAGTTTCGACTCTTACAAGAAAT:AAACGTTAAAAGTGGGAGACTGAGTA | |
V (18497) | (18440) |
Translocation | |
V (41740) | (41685) |
GGCCGCAAGGGCCAAGACAAG GAGTCTCCG: GAATTCAACGGTAAACGTGCAAGTG G | |
GATTTGTGTGGACTTCCTTAGAAGTAACCG:AAGCACAGGCGCTACCATGAG AAATG | |
XVI (856165) | (856220) |
For telomere addition, the number indicates the Saccharomyces Genome Database nucleotide coordinate of the last recognizable nucleotide of chromosome V before the added telomere sequences. For deletions and translocations, the numbers given above and below the sequences are the standard Saccharomyces Genome Database nucleotide coordinates for the first and last nucleotide listed with the Roman numeral indicating the chromosome number. The underlined nucleotides indicate those present in the translocation chromosome. The nucleotides in bold indicate identities.