Table 1. Frequency of SNPs in dyslexic subjects and controls.

		First sample set		Replication set		Combined
SNP	Coding change	Dyslexia % (n)	Control % (n)	Dyslexia % (n)	Control % (n)	P	OR (CI)
-164C → T	NC	6.4 (55)	3.2 (111)	1.0 (51)	1.8 (82)	0.3827	1.5 (0.6-3.9)
-3G → A	NC	8.3 (54)	3.1 (113)	8.7 (52)	2.5 (81)	0.0020	3.2 (1.5-6.9)
-2G → A	NC	0.9 (54)	0 (113)	0 (49)	1.3 (78)	0.7150	1.0 (0.1-10.7)
4G → T	P2S	0.9 (54)	0.5 (103)	0 (34)	2.3 (65)	0.8748	0.5 (0.1-4.4)
270G → A	V90I	1.9 (54)	5.3 (113)	8.2 (49)	5.0 (80)	0.9248	1.0 (0.4-2.1)
572G → A	G191E	51 (46)	47 (98)	44 (16)	44 (18)	0.6447	1.1 (0.7-1.7)
1249G → T	E417X	13.2 (53)	5.8 (113)	10.2 (54)	5.0 (80)	0.006	2.3 (1.2-4.2)
1259C → G	S420C	9.3 (43)	7.1 (106)	10.0 (35)	2.0 (25)	0.1610	1.7 (0.8-3.5)

The percentages are allele frequencies; n, number of subjects. Comparisons with P values <0.05 are in boldface. NC, noncoding change; OR, odds ratio; CI, 95% confidence interval.