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. 2003 Sep 22;100(20):11571–11576. doi: 10.1073/pnas.2035077100

Table 1. Genotypic identity at MHC class I and II loci by cDNA sequencing.

% nucleotide sequence homology
MHC class I loci
MHC class II loci
Strain H2-K H2-D H2-Aα H2-Aβ H2-Eα H2-Eβ
H2b haplotype
    GenBank strain C57BL/10 C57BL/10 129 NA NA B6
    B6 100 100 100 100 100
    BALB.B 100 100 100 100 100
H2k haplotype
    GenBank strain C3H C3H A/J B10.A NA B10.A
    AKR/J 100 100 100 100 100 100
    B10.BR 100 100 100 100 100 100
    BALB.K 100 100 100 100 100 100

MHC locus-specific PCR amplicons from cDNA templates spanning exons 2-4 (class I genes) and exons 2-3 (class II genes) were directly sequenced in both forward and reverse directions. Shown is percent nucleotide sequence homology for each mouse strain with a GenBank sequence at each locus. Reference cDNA sequences were not available for H2-Aβb, H2-Eαb, and H2-Eαk; H2-Eα is not expressed in H2b haplotype strains. Percent homology at the H2-Aβb and H2-Eαk loci represents interstrain comparison of mice used in this study. NA, not available.