Table 1. Linkage of B10.Q/J phenotype to chromosome 9.
Locus | Map distance, cM* | LOD score† |
---|---|---|
Tyk2/Aval | 0.0 | 53.3 |
D9Mit328 | 17.0 | 22.1 |
D9Mit192 | 17.7 | 21.4 |
D9Mit191 | 19.3 | 19.9 |
D9Mit330 | 21.9 | 17.8 |
D9Mit71 | 23.6 | 16.5 |
D9Mit4 | 25.4 | 15.3 |
Map distance was calculated by using mapmaker 3.0 (Roswell Park Cancer Institute, Buffalo, NY) on the basis of Haldane function, which assumes no interference (multiple crossovers according to a Poisson distribution).
LOD score calculation was based on two-point linkage analysis by using mapmaker 3.0 with LOD threshold of 3.0 and distance threshold of 80 Haldane cM.