Table 2.

Neurotrophins did not alter the inactivation properties of calcium currents in PC12nnr5 cells

	% prepulse inactivation	n
Control (NGF)	10  ± 4	12
TrkA + NGF	15  ± 2	21
Control (BDNF)	15  ± 3	15
TrkB + BDNF	14  ± 4	14
Control (NT-3)	16  ± 5	16
TrkC + NT-3	10  ± 5	10

Prepulse inactivation of LVA-type calcium channels, a measure of their contribution to the total calcium current, was not significantly different in neurotrophin-treated cells versus controls (mean ± SE, P > 0.2 for all groups). The degree of inactivation was measured as the percent change in current amplitude elicited by a depolarizing pulse following a −40 mV prepulse relative to a −120 mV prepulse.