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. 2003 Sep 18;100(20):11660–11665. doi: 10.1073/pnas.1832124100

Table 2. Comparative distribution of ORF function among selected free-living organisms.

cv* bs* ec* dr* tm* pa* sc* xcc* pp*
cog categories
    C, energy production and conversion 204 168 275 110 109 305 345 182 299
4.6% 4.0% 6.4% 4.1% 5.8% 5.5% 4.4% 4.4% 6.7%
    D, cell division and chromosome partitioning 41 34 34 19 18 32 46 39 48
0.9% 0.8% 0.7% 0.7% 2.8% 0.6% 0.6% 0.9% 1.1%
    E, amino acid transport and metabolism 334 291 350 202 177 477 425 229 491
7.5% 7.0% 8.1% 7.6% 9.5% 8.6% 5.4% 5.5% 11.1%
    F, nucleotide transport and metabolism 79 82 87 69 49 101 102 63 85
1.8% 1.9% 2.0% 2.6% 2.6% 1.8% 1.3% 1.5% 1.9%
    G, carbohydrate transport and metabolism 205 289 367 95 160 223 539 217 242
4.6% 7.0% 8.5% 3.6% 8.6% 4.0% 6.9% 5.2% 5.5%
    H, coenzyme metabolism 152 106 123 66 47 150 172 115 164
3.4% 2.5% 2.8% 2.5% 2.5% 2.7% 2.2% 2.7% 3.7%
    I, lipid metabolism 118 88 83 72 24 195 213 109 162
2.7% 2.1% 1.9% 2.7% 1.2% 3.5% 2.7% 2.6% 3.6%
    J, translation, ribosomal structure, and biogenesis 168 243 258 211 178 326 205 162 171
3.7% 5.9% 6.0% 8.0% 9.5% 5.9% 2.6% 3.9% 3.9%
    K, transcription 270 289 280 118 73 447 713 187 392
6.1% 7.0% 6.5% 4.4% 4.6% 8.0% 9.1% 4.5% 8.9%
    L, DNA replication, recombination, and repair 143 133 220 119 87 140 233 252 240
3.2% 3.2% 5.1% 4.5% 0.9% 2.5% 3.0% 6.0% 5.4%
    M, cell envelope biogenesis, outer membrane 222 178 235 78 70 257 258 217 244
5.0% 4.3% 5.4% 2.9% 3.7% 4.6% 3.3% 5.2% 5.5%
    N, cell motility and secretion 255 54 107 11 56 141 68 183 177
5.8% 1.3% 2.5% 0.4% 3.0% 2.5% 0.9% 4.4% 4.0%
    O, Posttranslational modification, protein turnover, chaperones 134 98 128 89 52 182 159 148 158
3.0% 2.3% 2.9% 3.3% 2.8% 3.3% 2.0% 3.5% 3.6%
    P, inorganic ion transport and metabolism 159 161 191 81 69 293 195 187 233
3.6% 3.9% 4.4% 3.0% 3.7% 5.3% 2.5% 4.5% 5.3%
    Q, secondary metabolites biosynthesis, transport, and catabolism 130 88 68 44 18 173 290 122 181
2.9% 2.1% 1.5% 1.6% 0.9% 3.1% 3.7% 2.9% 4.1%
    R, general function prediction only 358 348 338 241 191 491 609 332 458
8.0% 8.6% 7.9% 9.1% 10% 8.8% 7.8% 7.9% 10.4%
    S, function unknown 250 308 309 220 130 459 299 209 329
5.6% 7.4% 7.2% 8.3% 7.0% 8.2% 3.8% 5.0% 7.4%
    T, Transduction mechanisms 304 121 134 75 50 233 390 194 345
6.4% 2.9% 3.1% 2.8% 2.6% 4.2% 5.0% 4.6% 7.8%
    Not in cogs 1162 1033 692 709 300 942 2564 1035 931
24% 25% 16% 26% 16% 16.9% 32.8% 24.8% 17.4%
Total no. of ORFs 4431 4112 4279 2629 1858 5567 7825 4182 5350
Genome size, Mb 4.75 4.21 4.64 2.65 1.86 6.26 8.67 5.08 6.18
ORFs/100 kb 93.22 97.56 92.25 99.30 99.90 88.88 90.33 82.44 86.54
*

cv, C. violaceum; bs, Bacillus subtilis; ec, Escherichia coli; dr, Deinococcus radiodurans; tm, Thermotoga maritima; pa, P. aeruginosa; sc, Streptomyces coelicolor; xcc, Xanthomonas campestris citrus; pp, Pseudomonas putida.