Figure 1.

Sequence of the novel β2 and γ2 subunit of XENaC. The deducted amino acid sequences of the β2 and γ2 isoforms are aligned with the corresponding β and γ XENaC subunits [output of the pileup program of the Genetics Computer Group sequence analysis software package (18)]. Dots indicate that the residue in the β isoform is identical to the same position in the β2 isoform, and similarly for the γ and γ2 subunits. A dash indicates that a gap was introduced for obtaining a best-fit alignment. Lines above sequences indicate the positions of the putative transmembrane segments.