Table 3.
Relation of MMP-1 genotypes to clinical parameters and environmental factors among the OSCC cases
| 2G/2G n (%) | 1G/2G n (%) | 1G/1G n (%) | p | |
| Total | 77 (45.3) | 79 (46.5) | 14 (8.2) | |
| Gender | ||||
| Male | 46 (45.9) | 53 (47.5) | 8 (7.4) | 0.57 |
| Female | 31 (47.2) | 26 (41.3) | 6 (7.5) | |
| Age | ||||
| (years ± SD) | 54.8 ± 15.1 | 57.5 ± 13.2 | 60.1 ± 10.9 | 0.277* |
| T category | ||||
| T1-2 | 55 (45.1) | 58 (47.5) | 9 (7.4) | 0.78 |
| T3-4 | 22 (45.8) | 21 (43.8) | 5 (10.4) | |
| N category | ||||
| N0 | 50 (43.9) | 53 (46.5) | 11 (9.6) | 0.607 |
| N1-3 | 27 (48.2) | 26 (46.4) | 3 (5.4) | |
| Tumor location | ||||
| Tongue | 45 (54.9) | 31 (37.8) | 6 (7.3) | 0.260# |
| Lower gingiva | 14 (35) | 24 (60) | 2 (5) | |
| Oral floor | 6 (35.3) | 9 (52.9) | 2 (11.8) | |
| Buccal mucosa | 3 (21.4) | 9 (64.3) | 2 (14.3) | |
| Upper gingiva | 7 (53.8) | 5 (38.5) | 1 (7.7) | |
| Palate | 2 (50) | 1 (25) | 1 (25) | |
| Alcohol intake | ||||
| Drinker | 45 (45.9) | 45 (45.9) | 8 (8.2) | 0.982 |
| Non-drinker | 32 (44.4) | 34 (47.2) | 6 (8.3) | |
| Smoking status | ||||
| Smoker | 39 (44.3) | 43 (48.8) | 6 (6.8) | 0.702 |
| Non-smoker | 38 (46.3) | 36 (43.9) | 8 (9.8) |
T and N categories were according to the UICC TNM classification of malignant tumors for lip and oral cavity. The data were analyzed by the χ2.
* One-way ANOVA test.
# Fisher's exact tests.