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(A) Sequence of the PRT1 protein. Underlined in black, two RING finger domains; underlined in gray, ZZ domain. (B) Alignment of RING finger domains of several proteins with potential function in ubiquitin conjugation. RING 1, 2: RING finger domains of PRT1. RAD18, HRD1, APC11: RING finger domains of yeast proteins Rad18p, Hrd1p, and Apc11p, respectively. To optimize alignment, a maximum of three gaps were allowed per sequence (indicated by dots).
