Primary sequence and secondary structure of the cytohesin-1 Sec7 domain. Local 1H homonuclear NOE restraints [dNN(i, i+1), dαN(i, i+3), dαN(i, i+4), dαβ(i, i+3)] and deviations from random coil chemical shifts for 13Cα and 13C′ that define the secondary structure are indicated (38).