Figure 3.

Effect of adding exogenous sPLA₂ to P388D₁ cells. (A) Either resting (open bars) or LPS/PAF-activated (crosshatched bars) cells were incubated with the indicated concentrations of exogenous sPLA₂, and sPLA₂ surface expression was determined by flow cytometry. (B) PGE₂ production by resting (○) or LPS/PAF-activated (•) P388D₁ cells in the presence of the indicated concentrations of exogenous sPLA₂. Exogenous sPLA₂ was added at the time the cells were exposed to PAF or vehicle, and was present for 10 min.