Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Mutant SRP RNAs used in this investigation. ΔH6, ΔH8, and Δ35 were described previously (21); ΔL21 was constructed as detailed in Materials and Methods and was kindly provided by C. Zwieb. ΔL21 consists of the region within the Alu domain that is the binding site for SRP9 and SRP14 proteins. Δ35 corresponds to the S domain. ΔH6 is the complete SRP RNA lacking only helix 6, and ΔH8 is the complete SRP RNA lacking only helix 8.
