Figure 1.

Representative immunohistochemistry of acute skin-biopsy specimens of patient AF. (a and b) Staining of acute AGEP skin lesion with HE is shown. (a) ×100. (b) ×400. For immunophenotyping of acute lesions stainings of (c) CD4, (d) CD8, (e) neutrophil elastase, and (f) eosinophil marker EG2 are demonstrated. Activation of infiltrating cells and tissue is shown by (g) HLA-DR and by (h) CD25 staining. (i–l) Cytokine and chemokine production is shown for IL-5, IL-8, eotaxin, or RANTES. (c–l) ×250.