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Drug-specific proliferation of patients’ PBMCs in a lymphocyte transformation test. PBMCs (2 × 106) of patients were coincubated with different drugs for 6 days. Proliferation was then detected by 3H-thymidine incorporation. Drugs administered were: patients AP and JS, amoxicillin; patient AF, SMX; patient EB, celecoxib. SI is given as cpm of stimulated culture divided by cpm of unstimulated culture.
