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. 2001 Jul 1;108(1):97–105. doi: 10.1172/JCI12584

Figure 6.

Figure 6

Core temperature profile and IBAT UCP1 mRNA in mice kept in a cold environment (4°C) for 8 hours. The hypothyroid mice were treated with vehicle, T3 (7.2 ng/g/day) or GC-1 (3.6 ng/g/day) for 10 days and then transferred to a cold room. Animals were treated as described in the legend to Figure 2. (a) Core temperature response to cold exposure (4°C). Core temperature was measured with a rectal probe at indicated times. (b) Northern blot analysis of UCP1 mRNA from IBAT in euthyroid control and hypothyroid animals treated with vehicle, T3, or GC-1. Values are the mean ± SD of three to four mice. *P < 0.05 vs. control animals; **P < 0.05 vs. hypothyroid animals, by one-way ANOVA.