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. 2001 Aug 1;108(3):467–475. doi: 10.1172/JCI11895

Figure 2.

Figure 2

Hepatic GHR mRNA levels(a), but not protein abundance(b) or GH membrane binding(c), are reduced in CRF. Hepatic GHR mRNA was measured by Northern blot analysis and GHR protein by Western immunoblot analysis. Specific binding of radiolabeled bGH to receptors in purified liver plasma membranes and microsomes was measured by displacement with an excess of unlabeled bGH. All measurements were made in livers from the same animals. Data are expressed relative to PF vehicle-treated control mean value, assigned a value of 100. Bars indicate mean ± SEM. n = 4–6 rats/group. *P < 0.05.