Figure 11.
Leukocyte accumulation at day 7 after transplant. Analysis of immunoperoxidase-stained cell populations showed significant reductions (*P < 0.01) in recruitment of intragraft CD45+ cells (all leukocytes); T cells (CD3); CD4 and CD8 T cell subsets; macrophages and IL-2R+ (CD25+) cells in CX3CR1–/– animals treated with CsA vs. each of the other three groups. (Mean ± SD, 20 consecutive fields per graft and three grafts per group.)