Table IV.
GSNOR haplotypes in relation to childhood asthma risk.
| Relative risk (95% CI)
|
|||
|---|---|---|---|
| Haplotype a | Frequency | Single Copy | Double Copy |
| ht1 (GTCGG) | 0.418 | 1.14 (0.87–1.51) | 1.57 (1.09–2.30) b |
| ht2 (GACGA) | 0.328 | 0.84 (0.65–1.10) | 0.80 (0.52–1.21) |
| ht3 (CTCAA) | 0.073 | 1.19 (0.84–1.67) | 0.45 (0.06–3.26) |
| ht4 (CTTAA) | 0.061 | 0.91 (0.62–1.34) | 0.64 (0.08–4.45) |
| ht5 (GTCGA) | 0.057 | 1.13 (0.76–1.67) | 0.62 (0.08–4.99) |
a
The haplotypes formed by rs1154401G>C, rs1154404T>A, rs1154410C>T, rs1154412G>A, rs28730619A>G in order.
b
P = 0.017; false discovery rate = 0.02. For FBAT users, the P value from the additive model was 0.011.