. Author manuscript; available in PMC: 2008 Nov 15.

Published in final edited form as: Bioorg Med Chem. 2007 Aug 22;15(22):7042–7047. doi: 10.1016/j.bmc.2007.07.041

Table 1.

Comparison of the Inhibition Properties for the Quaternary Ammonium Catechol Based Inhibitors.

Inhibitor	IC₅₀ (μM)	K_I (μM)	Inhibition Classification
1^a	28	17	Noncompetitive
4^a	118	67	Mixed
5^a	15	3	Mixed
6^b	76	73	Mixed
7^b	21	31	Mixed
8^c,^d	6.8–15	-	Competitive
9^e,^d,^f	0.02–0.08	-	Competitive

reference ¹¹, ¹⁹.

this work.

references 13, 16, 29.

values for 8 and 9 are not readily KI comparable from the literature.

references 13–16, 28, 29.

references 12, 30.