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. 2007 Sep 3;35(18):6103–6114. doi: 10.1093/nar/gkm655

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© 2007 The Author(s)

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 4. — Description of the loop–loop Interaction of TAR/LR06(GA) and comparison to LNA/RNA and RNA/RNA complexes. (A) View of the loop–loop interaction of TAR/LR06(GA) with LNA residues, C9* and A10*, coloured in yellow. View of the minor groove water accessible surface of (B) TAR/LR06(GA) loop–loop helix, (C) an A-type helix, (D) TAR/TAR*(UA) (1KIS), (E) LNA:RNA hybrid (1HOQ) and (F) SL1 HIV-1 dimer loop–loop helix (2F4X). The surfaces are generated using a water probe of 1.4 Å radius on MOLMOL software. PDB ID are indicated in brackets.