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. Author manuscript; available in PMC: 2007 Nov 26.
Published in final edited form as: Ann Hum Genet. 2007 May 29;71(Pt 6):762–771. doi: 10.1111/j.1469-1809.2007.00370.x

Table 3.

Gender-specific hazard ratios of IHD, separately for each of the three blood measures of dyslipidemia, other established risk factors of IHD and the three isoforms of the APOE gene

Trait Females Hazard Ratio (95% C.I.) Males Hazard Ratio (95% C.I.)
Blood Measure of Dyslipidemia
 HDL-C 2.45 *** 1.28
(1.66–3.60) (0.99–1.66)
 TG 1.54 *** 1.34 **
(1.20–1.97) (1.07–1.68)
 T-C 0.71 1.21
(0.48–1.06) (0.90–1.63)
Other Established Risk Factors
 Smoking 1.76 *** 1.59 ***
(1.36–2.29) (1.23–2.06)
 Diabetes 2.96 *** 1.59 **
(1.96–4.48) (1.13–2.24)
 Hypertension 1.29 1.72 ***
(0.96–1.74) (1.29–2.30)
ApoE Isoform Groups
 E2/2, E3/2 0.91 0.81
(0.62–1.34) (0.57–1.15)
 E3/3 1 1
(–) (–)
 E4/2, E4/3, E4/4 1.13 0.9
(0.86–1.49) (0.70–1.16)

Significant at the * α ≤ 0.05, ** α ≤ 0.01, *** α ≤ 0.001 level of probability.