Table 1.
Measured physiological parameters and CBF derived from fitting the measured temperature profiles to the theoretical model
Physiological Parameters |
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---|---|---|---|---|---|---|
Rat | pH | MABP, mmHg | Paco2 Torr | Pao2 Torr | Δ, cm | Derived CBF, ml·g-1·min-1 |
1 | 7.353 | 90 | 48.4 | 83 | 0.30 | 0.85 |
2 | 7.355 | 82 | 43.7 | 78 | 0.35 | 0.62 |
3 | 7.410 | 75 | 45.2 | 127 | 0.38 | 0.52 |
4 | 7.371 | 90 | 48.8 | 76 | 0.29 | 0.89 |
5 | 7.383 | 80 | 48.0 | 89 | 0.35 | 0.61 |
6 | 7.430 | 78 | 45.8 | 82 | 0.36 | 0.57 |
7 | 7.376 | 89 | 47.3 | 109 | 0.29 | 0.93 |
8 | 7.316 | 88 | 58.9 | 77 | 0.28 | 0.97 |
9 | 7.391 | 100 | 49.0 | 86 | 0.27 | 1.03 |
10 | 7.354 | 102 | 56.9 | 116 | 0.26 | 1.15 |
Average | 7.374 | 87 | 49.2 | 92 | 0.31 | 0.81 |
± SD | 0.032 | 9 | 4.9 | 18 | 0.04 | 0.22 |
Constants used in the model, Eq. 1, to calculate cerebral blood flow (CBF): tissue density (ρ) = 1.0 g/cm3, density of blood (ρb) = 1.05 g/cm3, specific heat of blood (cb) = 3.8 J·g-1·°C-1, tissue thermal conductivity (K) = 5.03·10-3W·cm-1·°C-1. Significant correlation of CBF with both mean arterial blood pressure (MABP) and arterial Pco2 (Paco2) was found (Eq. 4, R2 = 0.96). Pao2, arterial Po2; Δ, characteristic shielding length.