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Comparison of hypertonic- and SB203580-induced currents. Average current density for currents activated by hypertonic exposure (20 mM sucrose) or SB203580 (500 nM) was measured at –80 mV. Both hypertonic- and SB203580-induced currents were inhibited by inclusion of EGTA (5 mM, no added Ca2+) in the patch pipette solution, and by amiloride (100 μM) in the extracellular solution (P < 0.01).
