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Characteristic flow patterns in response to FeCl3 injury. After recording baseline carotid blood flow (phase 1), ultrasound flow-monitoring was interrupted and the FeCl3-impregnated filter paper was placed on the adventitia of the vessel for 3 minutes (phase 2). The filter paper was removed, and the flow recording was continued (phase 3). (a) WT mouse, (b and c) ob/ob mice, (d) ob/ob mouse 30 minutes after intraperitoneal injection of 0.6 mg/kg leptin.
