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. 2001 Nov 15;108(10):1475–1482. doi: 10.1172/JCI13763

Figure 3.

Figure 3

Effects of anti−IL-12 on endotoxin lethality in STAT4–/– mice. Survival was assessed in STAT4–/– mice receiving 300 μg preimmune rabbit IgG or 300 μg anti−IL-12 intravenously just prior to intraperitoneal administration of 3 mg/kg endotoxin. Those mice alive at day 7 were alive at day 15 (data not shown). For each group, n = 9. *P < 0.05 compared with mice receiving preimmune IgG.