Table 4 Longitudinal analyses of the association between decline in FEV1 from age 26 to 32 and CRP at age 26 and 32.
Outcome | Predictor | Covariates | n | Coefficient (95% CI) | p Value | |
---|---|---|---|---|---|---|
Fall in FEV1 (ml) | Age 26 log‐CRP | Sex, height | 766 | −3.30 (−25.1 to 18.5) | 0.77 | |
Sex, height, smoking*, asthma* | 765 | −2.55 (−24.4 to 19.3) | 0.82 | |||
Age 32 log‐CRP | Fall in FEV1 (litres) | Sex, height | 788 | 0.48 (0.25 to 0.71) | <0.001 | |
Sex, height, smoking*, asthma*, age 26 CRP | 739 | 0.49 (0.26 to 0.71) | <0.001 |
CRP, C‐reactive protein; FEV1, forced expiratory volume in one second.
CRP values were log transformed for analysis and are expressed as standard deviation scores. Analyses exclude women who were pregnant at either age. *Analyses adjusted for history of smoking between age 26 and 32 years and current asthma diagnosis at either age.