Table 1. Descriptive demographical and clinical data of the symptomatic group (HD), presymptomatic group (pHD) and control group (controls).
HD | pHD | Controls | |
mean (SD) range | mean (SD) range | mean (SD) range | |
Sample size | N = 11 | N = 14 | N = 12 |
Male∶female ratio | 6 m∶5 f | T m∶7 f | 6 m∶6 f |
Age (years) | 36.50 (10.20) 21–57 | 35.91 (10.03) 22–52 | 36.50 (8.64) 23–52 |
CAG-repeat length | 47.10 (5.42) 40–56 | 42.58 (1.78) 39–46 | NA |
Age of onset (AO) | 34.20 (11.51) 17–56 | NA | NA |
Estimated age of onset (eAO) | 36.99 (11.39) 21–52 (N = 9) | 45.53 (4.62) 37.5–53.3 | NA |
Duration until eAO | −0.12 (7.94) −11.5–13.71 (N = 9) | 10.13 (8.19) −3.44–23.82 | NA |
UHDRS (motor score) | 26.00 (12.1) 9–44 | 0 | NA |
TFC | 11.70 (1.25) 9–13 | 13 | NA |
IS | 86.50 (8.83) 70–100 | 100 | NA |
IQ | 105.70 (7.66) 95–118 | 109.50 (11.86) 95–130 | 113.25 (8.86) 98–130 |
UHDRS (cognitive score) | 165.40 (24.05) 137–215 | 236.50 (16.81) 209–259 | 249.50 (11.03) 236–266 |
MMSE | 27.30 (2.26) 23–30 | 29.41 (0.51) 29–30 | 29.66 (0.5) 29–30 |
BDI | 5.90 (4.06) 0–13 | 5.75 (4.43) 0–14 | 3.00 (3.43) 0–12 |
YMRS | 3.30 (1.56) 1–5 | 1.33 (1.37) 0–4 | 1.36 (1.50) 0–5 |