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. 2001 Nov 1;108(9):1307–1314. doi: 10.1172/JCI12877

Figure 6.

Figure 6

VLA-4 is responsible for chemokine-mediated MM6 arrest on early atherosclerotic endothelium. (a) Blocking VLA-4 (mAb HP1/2), but not CD18 (mAb IB4), blocks MM6 cell arrest on early atherosclerotic endothelium (*P < 0.01, mean ± SEM, n = 3). (b) Increased MM6 cell arrest after KC perfusion is also inhibited by mAb HP1/2, but not IB4 (*P < 0.01, mean ± SEM, n = 3). (c) Blocking VLA-4 (mAb PS/2) or VCAM-1 (mAb MK2/7), but not CD18 (mAb GAME-46) or ICAM-1 (mAb YN1), inhibits mouse blood monocyte arrest on early atherosclerotic endothelium (*P < 0.01, mean ± SEM, n = 3).