. Author manuscript; available in PMC: 2007 Nov 26.

Published in final edited form as: Autoimmun Rev. 2007 Jan 12;6(6):387–401. doi: 10.1016/j.autrev.2006.12.005

Table 3.

VH gene family distribution in peripheral B cells from SLE and SS patients and healthy controls

	Expected frequency	2 Normal CD5- /IgM⁺ B cells [33]		1 SLE patient [29]		1 SS patient [39]
		non-productive (%)	Productive (%)	non-productive (%)	Productive (%)	non-productive (%)	Productive (%)
VH1	21.6	4.0	13.1^a	0	2.4	16.7	24.7
VH2	5.9	8.0	1.9	16.7	7.3	-	3.1
VH3	43.1	36.0	53.9^a	66.7	82.9^b	44.4	46.4
VH4	21.6	44.0^a	24.8	16.7	7.3^b	22.2	15.5
VH5	3.9	4.0	2.9	0	0	5.6	9.3
VH6	2.0	4.0	2.4	0	0	11.1	1.0
VH7	2.0	0	1.0	0	0	-	-

significantly different from expected frequency

significantly different from normal values

Bold numbers indicate significant differences between the productive and the non-productive repertoire Note that there were no significant differences between the productive and the non-productive repertoire of the SS patient or between either of these repertoires and those of healthy controls