Table 3.

Average scores for side effects recorded by physicians

Side effects	Group 1	Group 2	Group 3	P
Mucocutaneous
Dryness in mouth	0.09	0.05	0.47	0.001
Dry, chapped lips	0.71	1.16	1.95	<0.001
Dry skin	0.59	0.67	0.76	0.461
Dry or irritated eyes	0.09	0.05	0.16	0.275
Dryness of other mucosal tissues	0.00	0.05	0.21	0.026
Pruritus	0.14	0.16	0.37	0.064
Rash or facial redness	0.05	0.32	0.47	0.004
Epistaxis	0.00	0.00	0.11	0.361
Peeling of fingertip skin	0.00	0.11	0.32	0.056
Other
Fatigue	0.00	0.00	0.05	0.422
Excessive thirst	0.14	0.26	0.16	0.623

Side effects were evaluated on a 4-point scale as none (0), mild (1), moderate (2) or severe (3)