MyD88 KO mice exhibit defects in the induction of several proinflammatory mediators. MyD88 KO and WT mice (n = 4 or 5 per group) were sacrificed 1 day following S. aureus infection, whereupon IL-1β, MIP-2, and MCP-1 protein levels were quantitated by ELISA (mean ± SD). Results were normalized to the amount of total protein recovered to correct for differences in abscess sampling size. Significant differences are denoted by asterisks (*, p < 0.05; **, p < 0.001). Results are representative of three independent experiments.