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. Author manuscript; available in PMC: 2008 Apr 1.
Published in final edited form as: J Immunol. 2007 Apr 1;178(7):4528–4537. doi: 10.4049/jimmunol.178.7.4528

FIGURE 5.

FIGURE 5

The expression of numerous cytokines and chemokines is attenuated in abscess-associated cells from MyD88 KO mice. Abscess-associated neutrophils (A), macrophages (B), and microglia (C) were recovered from the lesions of MyD88 KO and WT mice at 12 h following S. aureus infection as described in Materials and Methods. Cells were cultured overnight without additional stimulation and conditioned supernatants were analyzed for mediator expression by multiplex microbead array assays. The amount of each cytokine/chemokine was normalized based on total cell numbers and represents the mean ± SEM from three independent experiments. Significant differences in mediator expression between the various cell types recovered from MyD88 KO vs WT mice are denoted with asterisks (*, p < 0.05; **, p < 0.001).