TABLE 1.
Distribution of isolates with reduced susceptibility to penicillin (PenR) among Canadian Paediatric Society/Laboratory Centre for Disease Control Immunization Monitoring Program, Active (IMPACT) centres, 1991 to 1998
| Centre | 1991 | 1992 | 1993 | 1994 | 1995 | 1996 | 1997 | 1998 | Total |
|---|---|---|---|---|---|---|---|---|---|
| Vancouver | |||||||||
| PenR isolates | 1 (0)* | 1 | 2 | 2 | 1 | 3 (3) | 1 | 3 (2) | 14 (5)* |
| Total isolates | 40 | 23 | 29 | 22 | 30 | 42 | 37 | 44 | 267 |
| Calgary | |||||||||
| PenR isolates | 1 | 3 (1) | 2 (1) | 1 | 2 (1) | 2 (1) | 5 (4) | 0 | 16 (8) |
| Total isolates | 27 | 34 | 14 | 10 | 18 | 12 | 24 | 8 | 147 |
| Edmonton | |||||||||
| PenR isolates | - | - | - | - | 3 | 4 (2) | 4 | 2 | 13 (2) |
| Total isolates | - | - | - | - | 27 | 27 | 18 | 21 | 93 |
| Winnipeg | |||||||||
| PenR isolates | 1 | 1 | 0 | 1 | 1 | 0 | 3 | 1 | 8 (0) |
| Total isolates | 16 | 23 | 17 | 32 | 13 | 14 | 23 | 10 | 148 |
| Ottawa | |||||||||
| PenR isolates | 0 | 0 | 0 | 2 (1) | 0 | 2 | 1 | 1 | 6 (1) |
| Total isolates | 2 | 19 | 18 | 15 | 10 | 25 | 11 | 26 | 126 |
| Toronto | |||||||||
| PenR isolates | 0 | 2 | 1 | 1 | 4 | 2 (1) | 4 (1) | 8 (1) | 22 (3) |
| Total isolates | 24 | 22 | 25 | 22 | 38 | 27 | 36 | 34 | 228 |
| Montreal A | |||||||||
| PenR isolates | 1 | 1 (1) | 2 | 1 (1) | 4 | 1 | 5 (1) | 4 (2) | 19 (5) |
| Total isolates | 15 | 33 | 23 | 24 | 21 | 18 | 32 | 38 | 204 |
| Montreal B | |||||||||
| PenR isolates | 1 | 2 | 1 | 5 (2) | 1 | 5 (3) | 5 (2) | 13 (6) | 33 (13) |
| Total isolates | 45 | 55 | 29 | 59 | 21 | 42 | 48 | 62 | 361 |
| Quebec City | |||||||||
| PenR isolates | 0 | 0 | 1 | 2 (1) | 0 | 0 | 0 | 3 (1) | 6 (2) |
| Total isolates | 20 | 15 | 17 | 12 | 9 | 13 | 13 | 16 | 115 |
| Halifax | |||||||||
| PenR isolates | 0 | 0 | 0 | 1 | 0 | 0 | 2 (1) | 1 | 4 (1) |
| Total isolates | 8 | 17 | 16 | 30 | 25 | 18 | 14 | 15 | 143 |
| St John's | |||||||||
| PenR isolates | - | - | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Total isolates | - | - | 5 | 1 | 1 | 3 | 3 | 2 | 15 |
| All centres | |||||||||
| PenR isolates | 5 (0) | 10 (2) | 9 (1) | 16 (5) | 16 (1) | 19 (10) | 30 (9) | 36 (12) | 141 (40) |
| Total isolates | 197 | 241 | 193 | 227 | 213 | 241 | 259 | 276 | 1847 |
*
Number of isolates with reduced susceptibility (number with high level resistance)