TABLE 3.
Oxazolidinones | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Linezolid | Eperezolid | Vancomycin | Q/D | |||||||||
Bacteria | MIC50 | MIC90 | Range | MIC50 | MIC90 | Range | MIC50 | MIC90 | Range | MIC50 | MIC90 | Range |
Bacteroides fragilis | 4 | 4 | 0.5-8.0 | 8 | 16 | 4-16 | N/A | N/A | 4.0-8.0 | 2 | 16 | 1.0-16 |
Clostridium difficile | 2 | 8 | 2-8 | N/A | N/A | N/A | 1 | 2 | 0.5-4 | N/A | N/A | N/A |
Clostridium perfringens | 2 | 2 | 0.5-2.0 | 2 | N/A | N/A | 0.5 | 1 | 0.25-1 | 0.25 | 1 | N/A |
Fusobacterium species | 0.5 | 0.5 | 0.125-1.0 | 0.5 | N/A | N/A | 0.5 | 1 | 0.5-1.0 | N/A | N/A | N/A |
Peptostreptococcus species | 1 | 2 | 0.5-2.0 | 1 | 1 | 0.5-1.0 | 0.5 | 1 | 0.25-1.0 | 0.25 | 1 | N/A |