TABLE 3.
Fluoroquinolone | C-8 moiety | Highest 'no effect dose' (mg/kg) |
---|---|---|
Norfloxacin | C - H | >300 |
Ciprofloxacin | C - H | >300 |
Ofloxacin | C - OR | >300 |
Moxifloxacin | CH3OH | >300 |
Gatifloxacin | CH3OH | >100 |
Gemifloxacin | N | >100 |
Trovafloxacin | N | >100 |
Enoxacin | N | 100 |
Sparfloxacin | CF | 18 |
Lomefloxacin | CF | 10 |
Bay y 3118 | CF | 10 |
Clinafloxacin | CF | 10 |