TABLE 4.
Minimal inhibitory concentration (MIC) ranges (mg/L) of Neisseria gonorrhoeae reference strains *†
| Antibiotic | WHO B* | WHO C* | WHO F* | ATCC 49226† |
|---|---|---|---|---|
| Penicillin | 0.032–0.125 | 0.25–1.0 | 0.008–0.032 | 0.25–1.0 |
| Spectinomycin | 16.0–32.0 | 16.0–32.0 | 16.0–32.0 | 8.0–32.0 |
| Tetracycline | 0.125–0.25 | 0.5–1.0 | 0.25–0.5 | 0.25–1.0 |
| Erythromycin | 0.063–0.125 | 0.5–1.0 | 0.5–1.0 | 1.0–2.0 |
| Ceftriaxone | 0.002–0.008 | 0.008–0.032 | 0.00025–0.001 | 0.004–0.016 |
| Ciprofloxacin | 0.002–0.008 | 0.002–0.008 | 0.002–0.008 | 0.001–0.008 |
| Cefixime | 0.004–0.016 | 0.008–0.032 | 0.0005–0.002 | 0.004–0.032 |
| Azithromycin | 0.032–0.063 | 0.063–0.125 | 0.125–0.25 | 0.5–1.0* |
*MICs for the World Health Organization (WHO) strains were determined using GC medium base (Difco, USA) supplemented with 1% Kellogg's defined supplement. Ranges established by the National Microbiology Laboratory in Winnipeg, Manitoba. †Acceptable ranges of MICs as per National Committee for Clinical Laboratory Standards document M100-S13 (M7-A6), January 2003 (45)