TABLE 7.
Case-control study (all cases included)
| Characteristic | Unmatched, n (%) | Matched | ||
|---|---|---|---|---|
| Case | Control | Statistical test | ||
| Mean length of time | 11.6 | 6.1 | Kruskal-Wallis H test 73.5, P<10–8 | |
| CVC inserted, days | Needles | |||
| Intrinsic CVC | 142 (78.5) | 134 (73.6) | Not significant | |
| characteristics | ≥2 versus one lumen | 126 (69.2) | 111 (61.3) | Crude OR=11.1, matched OR=3.33, 95% CI 1.3 to 10.1, P=0.005 |
| Not impregnated* | 135 (74.6) | 139 (76.4) | Not significant | |
| Cuffs (neonates) | 8 (10.7) | 2 (2.7) | Not significant | |
| Insertion circumstances | 08:01–17:00 | 106 (58.6) | 102 (56.0) | Not significant |
| Midnight – 08:00 | 16 (8.8) | 19 (10.4) | Not significant | |
| Nonelective | 9 (4.9) | 12 (6.6) | Not significant | |
| Due to complication | 9 (5.0) | 13 (7.2) | Not significant | |
| Removal | Removed due to | 80 (54.4) | 7 (5.4) | Crude OR=370, matched OR=19.3, 95% CI 7.22 to 72.4, P<10–8 |
| suspected sepsis | ||||
| Replaced | 67 (36.8) | 15 (8.2) | Crude OR=69.4, matched OR=8.3, 95% CI 2.5 to 43.2, P=0.00001 | |
| CVC used for: | Antimicrobials | 137 (75.3) | 114 (62.6) | Crude OR=3.32, matched OR=1.82, 95% CI 1.13 to 3.00, P=0.006 |
| Total parenteral nutrition | 102 (56.0) | 47 (25.8) | Crude OR=31.2, matched OR=5.6, 95% CI 3.00 to 11.3, P<10–8 | |
| Hemodialysis | 9 (4.9) | 13 (7.2) | Not significant | |
| Immunosuppressed | Diabetes | 37 (20.3) | 23 (12.7) | Crude OR=2.49, matched OR=1.58, not significant |
| Chemotherapy | 11 (6.0) | 3 (1.7) | Crude OR=13.4, matched OR=3.67, 95% CI 0.97 to 20.47, P=0.03 | |
| Steroids | 33 (18.4) | 22 (12.5) | Crude OR=4.0, matched OR=2.0, 95% CI 0.93 to 4.57, P=0.04 | |
| Total | 63 (34.8) | 45 (26.9) | Not significant | |
| Dirty, contaminated or | 48 (27.3) | 28 (15.8) | Crude OR=5.44, matched OR=2.33, 95% CI 1.24 to 4.6, P=0.003 | |
| clean/contaminated | ||||
| surgical wound | ||||
| Tracheostomy | 21 (11.5) | 9 (4.9) | Crude OR=6.25, matched OR=2.50, 95% CI 1.05 to 6.56, P=0.002 | |
| Intubated | 143 (79.0) | 148 (81.3) | Not significant | |
| Patient died | 40 (22.0) | 16 (8.8) | Crude OR=11.6, matched OR=3.40, 95% CI 1.64 to 7.7, P=0.0002 | |
*
Nonimpregnated central venous catheters (CVCs) were inserted for a mean of 9.5 days, compared with impregnated CVCs, which were inserted for a mean of 6.9 days (Kruskal-Wallis H test 6.0)