Figure 2.

HD phenotype is not caused by the absence of MHC class II products and is genetically unlinked to the class II locus. (a) PBLs from HD mice, normal littermates, and MHC class II-deficient mice were stained with antibody specific for the MHC class II I-A^b product. (b) F₂ progeny from the intercross between HD and BALB/c mice were stained with antibodies against CD4 and CD8. Data are shown for one mouse each of the HD phenotype that typed as H-2 b/b, b/d, or d/d.