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. 2007 Nov;66(Suppl 3):iii65–iii69. doi: 10.1136/ard.2007.078493

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Figure 4 T cell intrinsic defects as well as factors present in lupus sera contribute to the defective IL2 production characteristic of SLE T cells. The expression of NF‐κB subunits, as well as the inhibition of PP2A and CREM, lead to the correction of the IL2 production defect in T cells obtained from patients with lupus.