Table 1 Characteristics of subjects.
| Total | 270 subjects |
|---|---|
| Gender | 158 (58.5%) males, 112 females |
| Age (mean) | 66.7 (9.2) years |
| BMI (mean) | 31.5 (5.7) kg/m2 |
| Kellgren–Lawrence grade* (median, range) | 3 (0 to 4) |
| Baseline pain† (mean, SD) (0–100) | 44.2 (25.2) mm |
| Change in pain (mean, SD) from baseline to follow‐up | −1.9 (25.5) mm |
| Baseline synovitis score 0–9 | |
| Baseline infrapatellar fat pad score, 0/1/2/3 (%) | 21.5/40.0/33.9/4.6 |
| Baseline intercondylar notch score, 0/1/2/3 (%) | 31.5/52.3/15.0/1.2 |
| Baseline suprapatellar notch score, 0/1/2/3 (%) | 24.5/41.2/22.2/12.1 |
| Change in synovitis score | |
| Change in infrapatellar fat pad score, decrease/no change/increase (%) | 15.2/63.1/21.7 |
| Change in intercondylar notch score, decrease/no change/increase (%) | 14.3/66.8/18.9 |
| Change in suprapatellar notch score, decrease/no change/increase (%) | 20.4/59.2/20.4 |
| Baseline cartilage score in 14 plates (mean, SD) | 16.1 (9.2) |
| Baseline summary bone‐marrow lesion (mean, SD) | 3.2 (3.1) |
| Baseline effusion score (mean, SD) | 0.9 (0.8) |
*Subjects with “Knee pain/OA”, who had Kellgren–Lawrence grade 0 due to normal PA views, were defined as having radiographic OA due to definite osteophytes in patello‐femoral joint; †pain was measured on a 100‐mm visual analogue scale.