Table 1 Set‐up of the experimental groups.
Proteins (amount) used for immunisation | Rat strain (no. of animals) | Mouse strain (no. of animals) | No. of immunisations | LPS (mg/kg) |
---|---|---|---|---|
HPR3 (10 μg) | WKY (4) | C57BL/6J (4) | 2 | – |
mPR3 (10 μg) | WKY (4) | C57BL/6J (4) | 2 | – |
HHm (10 μg) | WKY (4) | C57BL/6J (4) | 2 | – |
HmH (10 μg) | WKY (4) | C57BL/6J (4) | 2 | – |
mHH (10 μg) | WKY (4) | C57BL/6J (4) | 2 | – |
mmH (10 μg) | WKY (4) | C57BL/6J (4) | 2 | – |
mHm (10 μg) | WKY (4) | C57BL/6J (4) | 2 | – |
Hmm (10 μg) | WKY (4) | C57BL/6J (4) | 2 | – |
Pool human/mouse PR3 (60 μg) | WKY (3)/BN (3) | – | 4 | – |
Pool human/mouse PR3 (60 μg) | WKY (3)/BN (3) | – | 4 | 1 |
Pool human/mouse PR3 (60 μg) | WKY (3)/BN (3) | – | 4 | 2.5 |
BSA (60 μg) | WKY (3)/BN (3) | – | 4 | – |
BSA (60 μg) | WKY (3)/BN (3) | – | 4 | 1 |
BSA (60 μg) | WKY (3)/BN (3) | – | 4 | 2.5 |