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. 2007 May 15;91(11):1512–1517. doi: 10.1136/bjo.2007.119453

Table 4 Sensitivities and specificities, with 95% confidence intervals (CI), for technical failures, any “disease” in patients with no technical failure, and referral for “full disease” grading.

Manual: by patient (CI) Automated: by patient (CI)
Technical failures Sensitivity 93.7% (91.3–95.4) 518/553 99.5% (98.4–99.8) 550/553
Specificity 99.0% (98.7–99.2) 6107/6169 84.4% (83.5–85.3) 5206/6169
Any “disease” in patients with no technical failure Sensitivity 83.8% (82.1–85.3) 1635/1952 85.5% (83.7–87.1) 1404/1643
Specificity 96.3% (95.6–96.8) 4000/4155 79.4% (78.1–80.7) 2830/3563
Referral for “full disease” grading Sensitivity 86.5% (85.1–87.8) 2182/2523 90.5% (89.3–91.6) 2283/2523
Specificity 95.3% (94.6–95.9) 4000/4199 67.4% (66.0–68.8) 2830/4199

Results are based on the analysis of images from both eyes of each patient.