Table 5 Sensitivities and specificities, with 95% confidence intervals (CI), for technical failures, any “disease” in patients with no technical failure, and referral for “full disease” grading.
| Manual: by eye (CI) | Automated: by eye (CI) | Automated: by image (CI) | ||
|---|---|---|---|---|
| Technical failures | Sensitivity | 89.1% (86.5–91.2) 596/669 | 98.4% (97.1–99.1) 658/669 | 97.0% (95.8–97.9) 950/979 |
| Specificity | 99.1% (98.9–99.2) 12 611/12 729 | 89.7% (89.2–90.2) 11 420/12 729 | 87.5% (86.9–88.1) 11 750/13 427 | |
| Any “disease” in patients with no technical failure | Sensitivity | 80.6% (79.1–81.9) 2475/3072 | 80.1% (78.6–81.5) 2224/2777 | 80.2% (78.7–81.6) 2296/2864 |
| Specificity | 95.5% (95.0–95.9) 9105/9539 | 87.8% (87.1–88.5) 7587/8643 | 87.9% (87.2–88.6) 7814/8886 | |
| Referral for “full disease” grading | Sensitivity | 82.7% (81.4–83.9) 3112/3764 | 85.2% (84.0–86.3) 3207/3764 | 86.2% (85.1–87.2) 3653/4237 |
| Specificity | 94.5% (94.0–94.9) 9105/9634 | 78.8% (77.9–79.6) 7587/9634 | 76.8% (76.0–77.7) 7814/10 169 | |
Results are based on the analysis of each eye and also of each individual image.