Table 3 Familial relations of myopia in multivariable regression using GEE2 method for different definitions of myopia.
| Manifest refraction | Cycloplegic refraction | |||
|---|---|---|---|---|
| Adjusted OR* (CI 95%) | λR | Adjusted OR (CI 95%) | λR | |
| Myopia ⩽−0.5 D | ||||
| Sibling–sibling | 3.42 (1.99 to 5.81) | 2.09 | 4.35 (1.97 to 9.58) | 2.58 |
| Parent–offspring | 2.56 (1.88 to 3.49) | 1.82 | 2.80 (1.88 to 4.22) | 2.05 |
| Spouse | 0.79 (0.51 to 1.22) | 0.84 | 0.68 (0.38 to 1.23) | 0.73 |
| Myopia ⩽−1 D | ||||
| Sibling–sibling | 3.93 (2.16 to 7.10) | 2.67 | 3.25 (1.75 to 5.99) | 2.46 |
| Parent–offspring | 3.03 (2.09 to 4.35) | 2.26 | 3.22 (2.09 to 4.95) | 2.45 |
| Spouse | 0.99 (0.57 to 1.75) | 0.99 | 1.19 (0.59 to 2.34) | 1.15 |
| Myopia ⩽−2 D | ||||
| Sibling–sibling | 4.39 (2.20 to 8.76) | 3.32 | 5.31 (2.43 to 11.59) | 3.86 |
| Parent–offspring | 3.53 (2.18 to 5.75) | 2.84 | 5.21 (3.03 to 9.03) | 3.81 |
| Spouse | 0.87 (0.35 to 2.18) | 0.88 | 1.02 (0.35 to 3.03) | 1.02 |
*All models were adjusted for age, sex, years of education, and height as possible confounding variables (data not shown).
CI, confidence interval; GEE2, second order generalised estimating equations; OR, odds ratio.