Table 2 Distribution of CRS suspect eye signs in clinical and laboratory‐confirmed patients.
| Eye signs | Suspects (n = 1090) | Clinically confirmed CRS (n = 299) | Odds ratio (95% CI) | MH χ2 (p value) | Laboratory‐confirmed CRS 46 | Odds ratio (95% CI) | MH χ2 (p value) |
|---|---|---|---|---|---|---|---|
| Microphthalmos | 193 | 54 | 1.03 (0.73 to 1.46) | 0.04 (0.85) | 14 | 2.11 (1.10 to 4.05) | 5.33 (0.02) |
| Cataract | 538 | 223 | 4.43 (3.24 to 6.06) | 104.78 (<0.0001) | 37 | 4.46 (2.11 to 9.39) | 18.54 (<0.0001) |
| Pupil rigidity | 159 | 61 | 1.81 (1.27 to 2.58) | 11.17 (0.0008) | 10 | 1.67 (0.81 to 3.44) | 1.97 (0.16) |
| Cloudy cornea | 151 | 28 | 0.56 (0.36 to 0.87) | 6.95 (0.008) | 9 | 1.55 (0.73 to 3.27) | 1.31 (0.25) |
| Corneal opacity | 160 | 32 | 0.62 (0.41 to 0.94) | 5.20 (0.02) | 3 | 0.39 (0.12 to 1.29) | 2.55 (0.11) |
| Microcornea | 263 | 91 | 1.57 (1.16 to 2.13) | 8.94 (0.003) | 24 | 3.67 (2.01 to 6.71) | 20.62 (<0.0001) |
| Iris hypoplasia | 148 | 65 | 2.37 (1.65 to 3.40) | 23.36 (<0.0001) | 11 | 2.08 (1.03 to 4.20) | 4.37 (0.04) |
| Glaucoma | 92 | 31 | 1.38 (0.88 to 2.18) | 1.98 (0.16) | 7 | 2.03 (0.88 to 4.67) | 2.85 (0.09) |
| Retinopathy | 63 | 49 | 10.88 (5.76 to 20.56) | 85.06 (<0.0001) | 6 | 2.60 (1.05 to 6.39) | 4.65 (0.03) |
| Optic Atrophy | 49 | 11 | 0.76 (0.38 to 1.50) | 0.64 (0.42) | 1 | 0.46 (0.06 to 3.42) | 0.60 (0.44) |
| Anophthalmos | 22 | 2 | 0.26 (0.06 to 1.12) | 3.79 (0.05) | 0 |