Table 1 Summary of KIT expression data for immunohistochemistry on a paediatric renal tumour tissue microarray.
Histology | KIT immunohistochemistry | ||
---|---|---|---|
Strongly positive | Weakly positive | Negative | |
FH WT | 8 (4.2%) | 25 (13.2%) | 156 (82.5%) |
Anaplastic WT | 0 | 2 (18.2%) | 9 (81.8%) |
CCSK | 3 (27.3%)* | 2 (18.2%) | 6 (54.5%) |
MN | 0 | 0 | 7 (100%) |
RTK | 0 | 1 (16.7%) | 5 (83.3%) |
PNET | 0 | 0 | 1 (100%) |
RCC | 0 | 0 | 1 (100%) |
A significantly increased proportion of CCSKs were positive compared to favourable histology Wilms' tumours (*p = 0.0206, Fisher's exact test).
WT, Wilms' tumour; FH, favourable histology; CCSK, clear cell sarcoma of the kidney; MN, mesoblastic nephroma; RTK, rhabdoid tumour of the kidney; PNET, primitive neuroectodermal tumour; RCC, renal cell carcinoma.