Table 2 Clinical correlations for KIT expression in favourable histology Wilms' tumours.
| Cell type | KIT immunohistochemistry | Immediate nephrectomy | Preoperative chemotherapy | Any | |||||
|---|---|---|---|---|---|---|---|---|---|
| Strongly positive | Weakly positive | Negative | RFS | OS | RFS | OS | RFS | OS | |
| WT blastemal | 5 (4.7%) | 13 (12.1%) | 89 (83.2%) | p = 0.69 | p = 0.52 | p = 0.08 | p = 0.16 | p = 0.14 | p = 0.67 |
| WT epithelial | 4 (5.7%) | 7 (10.0%) | 59 (71.4%) | p = 0.29 | NA | p = 0.031* | NA | 0.085 | NA |
| WT stromal | 0 | 7 (7.0%) | 93 (93.0%) | NA | NA | NA | NA | NA | NA |
| WT any | 8 (4.2%) | 25 (13.2%) | 156 (82.5%) | p = 0.21 | p = 0.42 | p = 0.0002* | p = 0.19 | p = 0.0044* | p = 0.45 |
Wilms' tumour cases from the tissue microarray are stratified according to cellular component. p Values are calculated for relapse‐free (RFS) and overall (OS) survival, stratified by treatment type.
*Significant associations.