Table 2 Gene expression changes in tumour tissues.
| Gene | Function | Array | Up/down |
|---|---|---|---|
| IL‐8 | Inflammation/angiogenesis | Cancer | Up (8) |
| Pai‐2 | Inhibitor of invasion | Cancer | Down (6) |
| Mmp1 | Invasion factor/protease | Cancer | Up (4) |
| Timp 1 | Inhibitor of mmp | Cancer | Up (3) |
| β‐catenin | Adhesion/proliferation | Cancer | Up (3) |
| Properdin | B‐factor | NFκB | Up (2) |
| Cyclin B1 | Mitosis promoting factor | Cell cycle | Up (2) |
| CDK1 | Mitosis promoting factor | Cell cycle | Up (2) |
| Cyclin G2 | Cell cycle protein | Cell cycle | Up (2) |
| Fos | Transcription factor | NFκB | Up (2) |
| ETS2 | Transcription factor | Cancer | Up (2) |
| Serpine B5 | Inhibitor of invasion | Cancer | Down (2) |
| Apaf 1 | Apoptosis | Cancer | Up (2) |
NF‐κB, nuclear factor‐κB.
List of common gene expression changes noted on the membrane arrays in the 11 adenocarcinoma tissues versus the 11 matched squamous tissues. Numbers in parentheses represent the number of tumour samples showing such up/down regulation. IL‐8 is up‐regulated in 8/11 (72%) tumours.