Figure 1 Metastasis from serous papillary carcinoma of the ovary: (A) typical papillary architecture; (B) less typical papillary architecture and (C) calcification. Immunohistochemical analysis shows expression of (D) Wilms' tumour 1 in tumour nuclei and vessels, (E) oestrogen receptor and (F) Ca125. Epithelial membrane antigen expression in (G) metastasis from serous papillary carcinoma of the ovary compared with (H) invasive micropapillary carcinoma of the breast.